Antibiotic resistance genes in swine manure slurry as affected by pit additives and facility disinfectants

Manure storage facilities are critical control points to reduce antibiotic resistance genes (ARGs) in swine manure slurry before the is land applied. However, little known about how exogenous chemicals entering may affect fate of ARGs. The objective this study was analyze impact six commonly used pit additives and four facility disinfectants on concentration ARGs slurry. Bench scale reactors, each containing approximately 50 L liquid manure, were dosed with or sampled for 40 days. Seven along intI1 gene 16S rRNA monitored. Out tested, Sludge Away significantly reduced time-averaged absolute abundance erm(C), erm(F), tet(Q), as compared no additive control. Tek-Trol erm(B), intI1, tet(X) than did no-disinfectant According Spearman's rank correlation, three showed a strong perfectly positive correlation two erm(B) tet(O) moderate both disinfectant tests. Overall, more effective controlling additives.